Sickle cell Diagnosis paper writing service

Sickle cell Diagnosis

 

1. What is the genetic basis of Sickle Cell anaemia (SCA)? (3 marks)

 

 

 

 

 

 

 

 

 

 

 

 

2. Why is DNA testing so useful in SCA diagnostics? (3marks)

 

 

 

 

 

 

 

 

 

 

 

 

 

3. How does the DNA analysis distinguish between normal and SCA patients ? (5marks)

 

 

 

 

 

 

4. Plot a standard curve using the known sizes of the bands in the ladder and determine the sizes of the DNA fragments obtained with the patient samples (attach this and a properly annotated figure of your gel to your submission) Enter the identity of the samples and the sizes of the fragments obtained in the box below (10marks)

 

 

 

5. What are the genotypes of the different samples? Explain how you determined this (6 marks)

 

6. .Outline any strengths of this diagnostic technique compared with others (5marks)

 

7. Outline any weaknesses of this diagnostic technique compared with others (5marks)

 

8. Describe one improvement you could make to this technique & explain its advantage (4marks)

 

 

 

 

9. What other test(s) might you perform to confirm your diagnosis and why? (3marks)

 

 

 

 

 

 

 

 

 

 

 

10. What treatment,if any, would you recommend for this child after birth? (4marks)

 

 

 

 

 

 

 

 

 

 

 

11. References                                                                                                                                                (2marks)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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