Normal human pregnancy and preeclampsia

Normal human pregnancy and preeclampsia

1) Pregnancy in human overall

2) development of normal placenta in human (hemochorial placentation explain and unique feature). try to use pic if useful and don’t forget labelling the pic and references it with explain it within the text.

3) Coagulation in normal pregnant
• Coagulation changes during the pregnancy and factors level and why
• Changes of coagulation in vitro (PT, APTT and thrombin generation) and vivo (D-Dimer and anti thrombin complex) tests.

4) Coagulation in embryology
• Coagulation in embryology in overall
• Development /activity and functional role of clotting factors in embryology
• What is effect at KO mice model

5) Preeclampsia
1) Definition
2) Pathogenesis. use pic if useful and don’t forget labelling the pic and references it with explain it within the text.
3) Epidemiology
• Descriptive epidemiology (morbidity data: incidence and prevalence in the world / Ireland specific) and (mortality Data world / Ireland specific) use graphs giving a picture of the and don’t forget labelling the pic and references it with explain it within the text.
• Analytical epidemiology – what are the main risk factors for the disease and how strong is the evidence for their association?
4) Sign and Symptoms
5) Causes
6) Diagnosis
• Laboratory measures (in vivo and and vitro) explain the method and normal references and the measures in the preeclampsia

7) Any New methods of detection (current state of the art)
8) Prevention
9) Management and treatment of preeclampsia
10) Complication (in foetus and mother)

references from Pubmed and research papers that should be free text as i need to read it

references should be up to 5 years ago ( not old )

make it significant acadimic writing and very excellent English.

 

 

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