WebMail 
hematology Case study
there are four hematology case studies, required to be answered all. Each case must be in one page. As well, no need for references. Please see the attachment file shows all the cases.
Kindness
BIO3107 Haematology 2.
Assignment 1. Case studies – Red Blood Cell Disorders
Case 1: C.J.D, a 15 year old female boarding school student taken to a local GP by her school nurse. The nurse reported that CJ is pale and appears to be “excessively tired”
Full blood count results.
| Parameter | Result | Reference range | |
| Haemoglobin | 60 g/L | 115-165 g/L | |
| Red blood cell count | 3.09 x 1012/L | 3.80-5.80 x 1012/L | |
| Haematocrit | 0.22 | 0.37-0.47 | |
| Mean cell volume | 80-100 fL | ||
| Mean cell haemoglobin | 26.5-33.0 pg | ||
| MCHC | 310-360 g/L | ||
| Reticulocyte count | 39.8 x 109/L | 20-80 x 109/L | |
| 1. Calculate and fill in the missing RBC indices (1 mark) | |||
| Blood film.
|
2. Describe the RBC morphology in C.J.D’s blood film. (1 mark)
|
||
| 3. Explain the significance of the reticulocyte count in this case.
(½ mark) |
|||
| 4. What is your provisional diagnosis based on the results of the FBC and the RBC morphology? (½ mark) | |||
| 5. What is the differential diagnosis in this case? (1 mark) | |||
| 6. What further laboratory investigations should be requested to rule out other possible disorders and confirm your diagnosis?
(½ mark) |
|||
|
7. Assuming that your provisional diagnosis is correct, describe the results you would expect from these confirmatory investigations. (1 mark) |
|||
| 8. What is the most likely root cause of this type of anaemia in a 15 year old girl? (½ mark) | |||
| 9. Describe the RBC morphology you would expect to see in blood taken from this patient at the completion of an appropriate 6 week course of treatment. (½ mark) | |||
Case 2: R.J.M, an 83-year-old man presents to his GP with shortness of breath and lethargy.
Full blood count results
| Parameter | Result | Reference range | |
| Haemoglobin | 49 g/L | 130-180 g/L | |
| Red blood cell count | 1.26 x 1012/L | 4.50-6.50 x 1012/L | |
| Haematocrit | 0.16 | 0.40-0.54 | |
| Mean cell volume | 80-100 fL | ||
| Mean cell haemoglobin | 26.5-33.0 pg | ||
| MCHC | 310-360 g/L | ||
| Reticulocyte count | 1.26 x 109/L | 20-80 x 109/L | |
| 1. Calculate and fill in the missing RBC indices. (1 mark) | |||
| Blood film
|
2. Describe the RBC morphology in RJM’s blood film. (1 mark)
|
||
| 3. What is your provisional diagnosis based on the results of the FBC and the RBC morphology? (½ mark) | |||
| 4. What further laboratory investigations should be requested to confirm your provisional diagnosis? (1 mark) | |||
Case 3. J.M.M, a 33-year-old female presents to the ED with abdominal pain and a history of gall stones.
Full blood count results
| Parameter | Result | Reference range | |
| Haemoglobin | 134 g/L | 115-165 g/L | |
| Red blood cell count | 3.87 x 1012/L | 3.80-5.80 x 1012/L | |
| Haematocrit | 0.35 | 0.37-0.47 | |
| Mean cell volume | |||
| Mean cell haemoglobin | |||
| MCHC | |||
| Reticulocyte count | 162.5 x 109/L | 20-80 x 109/L | |
| 1. Calculate and fill in the missing RBC indices. (1 mark) | |||
| Blood film
|
2. Describe the RBC morphology in J.M.M’s blood film. (1 mark) | ||
| 3. Explain the significance of the reticulocyte count in this case. (½ mark) | |||
| 4. What is the differential diagnosis in this case? (1 mark) | |||
| 6. What further laboratory investigations should be requested to enable a definitive diagnosis to be made? (1 mark) | |||
| 7. Why do patients with this type of anaemia frequently develop gall stones? (½ mark) | |||
Case 4. B.C.S, a 24-year-old male presents to ED with fever, rash and confusion.
Full blood count results
| Parameter | Result | Reference range | |
| Haemoglobin | 78 g/L | 130-180 g/L | |
| Red blood cell count | 2.44 x 1012/L | 4.50-6.50 x 1012/L | |
| Haematocrit | 0.23 | 0.40-0.54 | |
| Mean cell volume | 80-100 fL | ||
| Mean cell haemoglobin | 26.5-33.0 pg | ||
| MCHC | 310-360 g/L | ||
| Reticulocyte count | 178 x 109/L | 20-80 x 109/L | |
| White blood cell count | 12.2 x 109/L | 3.5-11.0 x 109/L | |
| Platelet count | 36 x 109/L | 150-400 x 109/L | |
| 1. Calculate and fill in the missing RBC indices. (1 mark) | |||
| 2. What is the likely cause of the rash in this patient and what is the name given to this type of rash? (1 mark) | |||
| Blood film
|
3. Describe the RBC morphology in B.C.S’s blood film. (1 mark)
|
||
| 4. What is the name given to this type of anaemia? (½ mark) | |||
| 5. Taking into consideration the clinical presentation, the FBC results and the RBC morphology, what is the most likely diagnosis in this case? (1 mark) | |||
| 6. What is your responsibility as a medical laboratory scientist when faced with a case like this? (½ mark) | |||
End of assignment 1.
Is this the question you were looking for? If so, place your order here to get started!
