Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.

Discussion:
Foundational Neuroscience
As a psychiatric nurse practitioner, it
is essential for you to have a strong background in foundational neuroscience.
In order to diagnose and treat patients, you must not only understand the
pathophysiology of psychiatric disorders but also how medications for these
disorders impact the central nervous system. These concepts of foundational
neuroscience can be challenging to understand. Therefore, this Discussion is
designed to encourage you to think through these concepts, develop a rationale
for your thinking, and deepen your understanding by interacting with your
colleagues.
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For this Discussion, review the Learning
Resources and reflect on the concepts of foundational neuroscience as they
might apply to your role as the psychiatric mental health nurse practitioner in
prescribing medications for patients.
By Day 3 of Week 2
Post a response to each of the following:
Explain the agonist-to-antagonist spectrum of action of
psychopharmacologic agents, including how partial and inverse agonist
functionality may impact the efficacy of psychopharmacologic treatments.
Compare and contrast the actions of g couple proteins
and ion gated channels.
Explain how the role of epigenetics may contribute to
pharmacologic action.
Explain how this information may impact the way you
prescribe medications to patients. Include a specific example of a
situation or case with a patient in which the psychiatric mental health
nurse practitioner must be aware of the medication’s action.

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